Spectrum: Local Antimicrobial Stewardship, for Markham Stouffville Hospital

Predisposing Conditions

Select Condition

Basilar Skull Fracture

Penetrating Trauma

Postneurosurgery

CSF Shunt

Important Note

If PCN-anaphylaxis for any of the above, use the following regimens

PCN-Anaphylaxis (Adults)

Moxifloxacin 400mg IV q24h

AND

Vancomycin 15mg/kg IV q8h

PCN-Anaphylaxis (Pediatrics)

Vancomycin (Meningitis-Specific Dosing)

PLUS EITHER

Rifampin(Meningitis-Specific Dosing)

OR

Meropenem(Meningitis-Specific Dosing)