Spectrum: Local Antimicrobial Stewardship, for Markham Stouffville Hospital

Postneurosurgery

Common Bacterial Pathogens

Aerobic Gram Neg. Bacilli (including Pseudomonas aeruginosa)

S. aureus

Coagulase-neg. Staph
(Especially S. epidermidis)

Empiric Antimicrobial Therapy

Vancomycin (Meningitis-Specific Dosing)

PLUS EITHER

Ceftazidime¹ (Meningitis-Specific Dosing)

OR

Meropenem (Meningitis-Specific Dosing)

Note¹

If Pseudomonas not documented at 72 hrs, may switch ceftazidime to ceftriaxone 2 g IV Q12H