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Guidelines
Pathogens
Antimicrobials
Coagulase-neg. Staph (Especially S. epidermidis)
S. aureus
Aerobic Gram Neg. Bacilli (including Pseudomonas aeruginosa)
P. acnes
Vancomycin (Meningitis-Specific Dosing)
PLUS EITHER
Ceftazidime¹ (Meningitis-Specific Dosing)
OR
Meropenem¹ (Meningitis-Specific Dosing)
¹ In infants and children, vancomycin alone is reasonable unless Gram stains reveal the presence of gram-neg. bacilli.
Rifampin may be considered in Staphylococcal shunt infections.
Rifampin (Meningitis-Specific Dosing)
