Spectrum: Local Antimicrobial Stewardship, for Billings Clinic

Purulent - Severe

Prior to Initiating Antibiotics

Incision and drainage

Preferred Empiric Treatment

Vancomycin per pharmacy

ALTERNATIVES

Linezolid*

Ceftaroline*

Daptomycin*

*Restricted antimicrobial agent at BC. Requires approval by ID provider.

REMINDER

Switch to defined antibiotics once culture and sensitivity results are available.

Defined Antibiotics

Vancomycin per pharmacy

For MRSA

OR

Cefazolin 2 g IV q8h

For MSSA

OR

Clindamycin 300 mg PO QID

  • If susceptibility is known

  • Empiric clindamycin is not recommended because MRSA resistance >30%