Spectrum: Local Antimicrobial Stewardship, for Billings Clinic

Purulent - Moderate

Prior to Initiating Antibiotics

Incision and drainage

Preferred Empiric Treatment

TMP/SMX 1-2 DS BID

OR

Doxycycline 100 mg BID

THEN

Switch to defined antibiotics once culture and sensitivity results are available.

Defined Antibiotics

TMP/SMX 1-2 DS BID

For MRSA

OR

Cephalexin 1000 mg PO TID

For MSSA

OR

Clindamycin 300 mg PO QID

  • If susceptibility is known

  • Empiric clindamycin is not recommended because MRSA resistance >30%