Low
Excellent
See Below
Urinary tract infections
MRSA infections
Stenotrophomonas infections
Pneumocystis jirovecii pneumonia (Treatment or prophylaxis)
Toxoplasmosis prophylaxis
Follow creatinine and electrolytes in patients at increased risk renal failure, hyperkalemia.
Gastrointestinal upset common
Bone marrow suppression
Hyperkalemia
Renal failure
Hepatitis
Aseptic meningitis
Stevens Johnson syndrome/toxic epidermal necrolysis
Other rashes
ACEi - Increased serum potassium level
Methotrexate - Marrow suppression
Increases phenytoin
Increases INR with warfarin
Antimicrobial class: Sulfonamide - Antifolate
Pregnancy category: D
Average serum half life: 10 hours
Biliary penetration: Moderate
CSF penetration: Therapeutic
Lung penetration: Therapeutic
Urine penetration: Therapeutic
