Spectrum: Local Antimicrobial Stewardship, for IWK Health Centre

Facial Cellulitis Secondary to a Dental Source

Microbiology

Most Likely Pathogens

Recommendation

Patient should be evaluated for source control (extraction and drainage)

Duration of Therapy

7 days

Empiric Regimen: Oral

Amoxicillin 16 mg/kg/dose PO TID

Maximum: 500 mg/dose

OR

Amoxicillin-Clavulanate 16 mg/kg/dose PO TID

  • Dosing is based on amoxicillin component

  • Use the 80 mg/mL (7:1) formulation only

  • Maximum: 500 mg/dose

Empiric Regimen: IV

Penicillin G 0.025 million units/kg/dose IV q6h

Maximum: 24 million units/24h

+/-

Metronidazole 10 mg/kg/dose IV q8h

Maximum: 500 mg/dose

Penicillin Allergy: Oral

Clindamycin 20-30 mg/kg/24h PO divided q6-8h

Maximum: 1.8 grams PO/24h

Penicillin Allergy: IV

Clindamycin 25-40 mg/kg/24h IV divided q6-8h

Maximum/dose: 900 mg/dose