Prophylaxis

Recommended in those that are/have:

• Moderate-severe injuries, especially to the hands, genitalia or face or if have injuries that may have penetrated the bone or joint

• Wounds in areas with underlying venous and/or lymphatic compromise

• Immunocompromised

• Asplenic

• Advanced liver disease

• Pre-existing or resultant edema of the affected area

• Deep puncture wounds or associated-crush injury