Pancreatitis Empiric Rx

Note

Patients with severe infection are at risk of abdominal compartment syndrome - monitor intrabdominal pressures if possible

Abdominal Compartment Syndrome

Abdominal compartment syndrome (ACS) is defined as intra-abdominal pressure >20mmHg and new organ failure (renal, pulmonary or hemodynamic).

If ACS is suspected, consult surgery

Duration of therapy depends on clinical course

In patients who fail to improve, surgical debridement of necrosis may be required and consultation with surgical team recommended

Meropenem 1g IV q8h or 500 mg IV q6h

If patient not responding to antibiotics and has Candida risk factors consider empiric Caspofungin 50mg IV q24h

Candida risk factors