Spectrum: Local Antimicrobial Stewardship, for Prisma Health Children’s Hospital-Midlands

AHOM Empiric Treatment

Consult

Pediatric Orthopedics

Infectious Disease

Obtain Baseline Labs

  • Blood Culture
  • BMP/CBC
  • CRP
  • ESR

Surgical Intervention

As recommended per Pediatric Orthopedics

First Line Treatment

Note: Dosing is for patients >28 days old with normal renal function

START PATIENT ON

Vancomycin

until sensitivities are available or cultures are negative at 48 hours

ADD*

Ceftriaxone

*For patients age 3 – 36 months

Monitoring

  • Repeat CRP every other day

  • Repeat CBC as clinically indicated

  • Repeat blood culture until negative

Note

When susceptibilities are available or at 48 hours if all cultures negative, de-escalate to narrowest spectrum antibiotic

Follow Up

Oral Stepdown and Discharge

Completing Therapy