Spectrum: Local Antimicrobial Stewardship, for Fraser Health

Post-op IAI: Mild-moderate infection

Duration

4-7 days

  • Patients with adequate source control procedure (e.g., surgery, IR drainage, ERCP) can have their antibiotics discontinued 4 days after the procedure.

  • Patients who DO NOT have adequate source control may require prolonged course of antibiotics dependent on clinical and radiographic response. Consider expert
    consultation.

Empiric Regimen

Piperacillin-tazobactam 3.375 g IV q6h

If MRSA suspected ADD:

Vancomycin

Severe Beta-Lactam Allergy

Ciprofloxacin 400 mg IV q12h

OR

If hemodynamically stable, able to swallow, and functioning GI tract:

Ciprofloxacin 500 mg PO BID

AND

Metronidazole 500 mg IV/PO q12h

If MRSA suspected ADD:

Vancomycin