Spectrum: Local Antimicrobial Stewardship, for Billings Clinic

Sinusitis - Pediatric

First Line Treatment

Amoxicillin 45 mg/kg/day in 2 divided doses x 10 days

OR

Amoxicillin-Clavulanate 45 mg/kg/day in 2 divided doses x 10 days

Risk for Antibiotic Resistance or Failed Initial Therapy

Amoxicillin 90 mg/kg/day in 2 divided doses (Use the 600 mg/5 mL formulation)

OR

Amoxicillin-Clavulanate 90 mg/kg/day in 2 divided doses (Use the 600 mg/5 mL formulation)

Beta-Lactam Allergy: Non-Type I Hypersensitivity

Clindamycin 30 mg/kg/day in 3 divided doses x 10 days

PLUS

Cefdinir 14 mg/kg/day in 2 divided doses x 10 days

Beta-Lactam Allergy: Type I Hypersensitivity

Levofloxacin
6m-5y: 20 mg/kg/day in 2 divided doses x 10 days
>5y: 10 mg/kg daily x 10 days