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Pathogens
Antimicrobials
Medium
Excellent
<$1/day
500-1000mg po TID
Empiric S. pneumoniae coverage 1000mg po TID
Therapy of Streptococcal and Enterococcal infections as well as susceptible gram negative infections.
Commonly used for respiratory infections and urinary tract infections.
Allergy/rash (immediate or delayed)
Note EBV related rash
Cytopenias
Allopurinol - increased rash
Good step down agent from IV ampicillin
Ampicillin susceptibility implies amoxicillin susceptibility
Oral amoxicillin has better tolerability and bioavailability than oral ampicillin
Antimicrobial class: Aminopenicillin
Pregnancy category: B
Average serum half life: 1 hour
Biliary penetration: Therapeutic
CSF penetration: Limited - use IV ampicillin for meningitis
Lung penetration: Therapeutic
Urine penetration: Therapeutic