Spectrum: Local Antimicrobial Stewardship, for IWK Health Centre

Lyme Arthritis

Consult Infectious Diseases

This is a manifestation of late disseminated Lyme disease

Infection Prevention and Control

Routine Practices

Most Likely Pathogen

Borellia burgdorferi

Duration of therapy

28 days

Suggested Regimen

For patients greater than or equal to 8 years of age

Doxycycline 2.2 mg/kg/dose PO BID
Round dose to nearest 25 mg (1/4 tablet)
Maximum: 100 mg/dose

OR

For patients less than 8 years of age

There are limited safety data on the use of doxycycline for greater than 21 days in children less than 8 years of age

Amoxicillin 16 mg/kg/dose PO TID
Maximum: 500 mg/dose

Penicillin Allergy

Cefuroxime 15 mg/kg/dose PO BID
Maximum: 500 mg /dose