Low
Excellent
$0.20/day
Lyme disease
Skin and soft tissue infection
Methicillin resistant staphylococcus aureus infections
GI upset (take with food to avoid)
Erosive esophagitis (drink plenty of water with dose)
Photosensitivity rash
Divalent cations- decreased absorption therefore recommended to space by 2 hours.
100 mg tablet (scored in quarters)
Tablets and capsules are preferred especially over an unpleasant tasting liquid.
Not all strengths of oral tablets/capsules are listed and they are not all available on the IWK formulary
Take with food to reduce GI upset.
Avoid iron, magnesium, calcium for at least two hours before or two hours after doxycycline administration.
Contraindicated in pregnancy; except for single dose (see Lyme Disease in pregnancy) and not routinely recommended in children <8 years of age except for treatment and prophylaxis for Lyme disease (see Lyme Disease pediatrics)
Antimicrobial class: Tetracycline
Average serum half life: No data for pediatrics.
Adults: 12 to 15 hours (usually increases to 22 to 24 hours with multiple dosing)
Route of Elimination: In the urine (23%) and feces (30%)
