Spectrum: Local Antimicrobial Stewardship, for Alberta Children's Hospital

Internal Fixation of Fractures or Prosthetic Joints

Suggested Regimen

Cefazolin IV 30 mg/kg

Pre-Op Administration

Direct IV

Intraoperative Re-Dosing Interval

q4h from time of pre-op dose

Penicillin Allergy/Anaphylaxis

Clindamycin IV 10 mg/kg

Pre-Op Administration

Administer over 30 minutes just prior to procedure

Intraoperative Re-Dosing Interval

q4h from time of pre-op dose