Candida | Spectrum

Notes

All patients with candidemia should have a dilated retinal examination by an ophthalmologist within the first week of therapy to establish if endophthalmitis is present.

For neutropenic patients, it is recommended to delay the examination until neutrophil recovery.

Antibiotic Regimen

Fluconazole 800mg (or 12mg/kg) IV or oral loading dose, then 400mg (or 6 mg/kg) IV or orally daily

Fluconazole is acceptable in patients who are not critically ill, had no azole exposure in previous 2 months, and are unlikely to have fluconazole resistant candida

OR

Caspofungin 70 mg IV loading dose then 50 mg IV daily

Catheters and Duration of Therapy

Short-Term Catheter

Remove catheter

Long-Term Catheter

Remove catheter

Duration of Therapy

14 days