Spectrum: Local Antimicrobial Stewardship, for Markham Stouffville Hospital

Empiric Therapy

Most likely Pathogens

Enterobacteriaceae

Anerobes

Enterococcus spp

S. aureus

CNST

Candida spp

Regimen of Choice

Ampicillin 2 g IV q6h

AND

Ceftriaxone 1 g IV q24h

AND

Metronidazole 500 mg IV q12h

OR

Piperacillin-tazobactam 4.5 g IV q8h

Duration of Therapy

Based on clinical improvement