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Guidelines
Pathogens
Antimicrobials
Enterobacteriaceae
Anaerobes
Viridans Group Streptococci
Beta-hemolytic Streptococci
Clindamycin 900 mg IV q8h
PLUS
Gentamicin 5-7 mg/kg IV q24h*
*If immediately postpartum (less than 7 days), use gentamicin 1.5-2 mg/kg q8h
Gentamicin Dosing Weight
PLUS**
Ampicillin 2 g IV then 1 g q4h
**If known to be colonized with GBS.
Ampicillin 2 g IV then 1 g IV q4h
Gentamicin 5-7 mg/kg IV q24h
Metronidazole 500 mg IV q8h
Parenteral therapy should be continued until patient clinically improved, no fundal tenderness and afebrile for 24-48h.
Stepdown to oral therapy thereafter is NOT beneficial.
Enterococcus spp.
Resistant Gram negative bacilli
References
Approval, Review and Revised Dates
Original Approval Date: 17/06/04
Reviewed Date: 03/05/12
Revised Date: 07/04/16