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Guidelines
Pathogens
Antimicrobials
Staphyloccocus aureus
MRSA Risk Factors:
Evidence of MRSA infection elsewhere
Nasal colonization with MRSA
Injection drug use
Streptococci spp
Gram negative organisms
Anaerobes
Ceftriaxone 2g IV Q24H
PLUS
Metronidazole 500mg PO Q12H
Use IV if unable to take PO
ALTERNATIVELY, CONSIDER
Piperacillin-Tazobactam 4.5g IV Q8H
ADD
Vancomycin (Dosing Below)
Adults
Vancomycin 15-20mg/kg Q8-12H
Pediatrics
Birth to 3 Months Vancomycin 15mg/kg IV Q6H
Over 3 Months Vancomycin 10mg/kg IV Q6H
