Spectrum: Local Antimicrobial Stewardship, for Bakersfield Memorial Hospital

Perforated, Stable

Empiric Therapy

Ceftriaxone 1 g IV every 24 hr

AND

Metronidazole 500 mg IV every 8 hr

Oral Stepdown

Amoxicillin/Clavulanate 875 mg PO BID

Cephalosporin Allergy

Levofloxacin 500 mg IV every 24 hr

PLUS

Metronidazole 500 mg IV every 8 hr

Duration

5 - 7 days