Spectrum: Local Antimicrobial Stewardship, for Eastern Health

Healthcare associated, late onset or critically ill

Duration of therapy

5-7 days

Recommended regimen

Piperacillin-tazobactam 3.375g IV q6h

Oral stepdown

Amoxicillin-clavulanate 875mg PO BID

Penicillin Allergy

Levofloxacin 750 mg PO/IV q24h

and

Metronidazole 500mg PO/IV q12h