Medium
NA
$12.16/day
Broad spectrum agent with anti-pseudomonal activity.
Used for severe infections including:
Pneumonia
Intra-abdominal/hepatobiliary
UTI
Polymicrobial skin and soft tissue infection
Febrile neutropenia
Patients on therapy for > 7 days should have (at least) weekly CBC due to risk of drug-induced neutropenia and thrombocytpoenia
Allergy/rash (immediate or delayed)
Cytopenias- esp. thrombocytopenia
Eosinophilia
Interstitial nephritis
Abnormal liver enzymes
IV Administration
Dilute in 100 mL D5W or NS and administer over 30-60 min.
EH Prescribing Restrictions
None
Community IV Formulary (Metro Area)
YES
Antimicrobial class: Ureidopenicillin with a beta-lactamase inhibitor
Pregnancy category: B
Average serum half life: 1 hour
Urine penetration: Therapeutic
Lung penetration: Therapeutic
CSF penetration: Poor
Biliary penetration: Therapeutic
