Spectrum: Local Antimicrobial Stewardship, for Eastern Health

Pancreatitis Directed Rx

Patients with severe infection are at risk of abdominal compartment syndrome - monitor intrabdominal pressures if possible

Abdominal Compartment Syndrome

Abdominal compartment syndrome (ACS) is defined as intra-abdominal pressure >20mmHg and new organ failure (renal, pulmonary or hemodynamic).

If ACS is suspected consult surgery.

Use culture results to guide therapy

Antibiotics With Good Pancreatic Penetration

Meropenem

Ciprofloxacin

Metronidazole

Fluconazole

Antibiotics With Reasonable Pancreatic Penetration

Piperacillin-tazobactam