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Pathogens
Antimicrobials
Duration of therapy after source control is 4-7d guided by resolution of fever, normal WBC, and benign abdomen.
Generally, longer duration of therapy for bacteremia.
Target therapy once biliary cultures available taking into account the pathogenic potential and amount of organism identified.
Piperacillin-tazobactam 3.375 gm IV q6h
OR
Meropenem 500 mg IV q6h or 1 gm IV q8h
Imipenem-Cilastin 500 mg IV q6h
Consider ID Consultation in the immunocompromised patient
Day 3 Bundle