Spectrum: Local Antimicrobial Stewardship, for Providence Health Care

Empiric Treatment

Most likely pathogens

IV

Ceftriaxone 1g IV q24h

+ / -

Vancomycin 25mg/kg IV loading dose x 1 dose followed by 15mg/kg IV with interval to be determined by vancomycin nomogram

View Vancomycin nomogram

Severe Penicillin Allergy (IV)

Moxifloxacin 400mg IV q24h

Oral Stepdown

Amoxicillin-clavulanate 875-125mg PO BID

Severe Penicillin Allergy (Oral)

Moxifloxacin 400mg PO daily