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Pathogens
Antimicrobials
High
NA
Ceftriaxone Usual Dose 1-2 gm IV q24h
Bacterial meningitis 2 gm IV q12h
Enterococcus faecalis endocarditis 2g IV q12h
Empiric therapy of bacterial meningitis
Empiric therapy of nosocomial Gram negative infections (except Pseudomonas)
Empiric therapy of hospitalized community or nursing home acquired pneumonia in combination with a macrolide
Empiric therapy of spontaneous bacterial peritonitis
Empiric treatment of pyelonephritis
Allergy/rash (immediate or delayed).
Cytopenias, eosinophilia, and hepatic and renal laboratory abnormalities
Pseudocholelithiasis- unclear clinical significance - uncommonly symptomatic, but frequently by ultrasound gallbladder sludge
Antimicrobial class: Parenteral Cephalosporin - 3rd Generation
Pregnancy category: B
Average serum half life: 8.0
Biliary penetration: Therapeutic
CSF penetration: Therapeutic
Lung penetration: Therapeutic
Urine penetration: Therapeutic