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Antimicrobials
Key messages
Clindamycin should not be used for empiric treatment due to increasing resistance
The listed oral antibiotics have excellent or very good bioavailability
MRSA coverage not required empirically except in critically ill patients with purulent head/neck infections including otitis externa
Pseudomonas coverage not required empirically except in otitis externa
Control the source of infection, and send appropriate specimens to the microbiology laboratory
Severe/malignant otitis externa
Suppurative parotitis
Acute bacterial sinusitis
Acute mastoiditis
Bacterial tracheitis
Epiglottitis
Orbital cellulitis
Rhinogenic/otogenic parapharyngeal infection
Rhinogenic/otogenic retropharyngeal infection
Odontogenic parapharyngeal/retropharyngeal infection
Peritonsillar abscess
Septic jugular thrombophlebitis (Lemierre syndrome)
Submandibular space (Ludwig's angina)
References
(1) Pocket Guide to Antimicrobial Therapy in Otolaryngology – Head and Neck Surgery, 13th Edition (American Academy of Otolaryngology)
(2) Infectious Diseases Society of America Clinical Practice Guideline for Acute Bacterial Rhinosinusitis in Children and Adults
(3) The Sanford Guide To Antimicrobial Therapy 2016, 46th Edition