Spectrum: Local Antimicrobial Stewardship, for Yangon Children's Hospital

Plasmodium knowlesi

Increased risk of hyperparasitaemia and complications

  • Due to short 24h life-cycle of parasite, increased risk of complications including severe malaria

  • Artemisinin-based combination therapy is an alternative treatment

Pathogen

Plasmodium knowlesi

Treatment

Chloroquine

  • Days 1 & 2: 10 mg/kg

  • Day 3: 5 mg/kg

OR

Artemisinin-based Combination

OR

Quinine Sulfate + Doxycycline/Tetracycline

OR

Atovaquone + Proguanil (Malarone)

OR

Mefloquine