Home
Guidelines
Pathogens
Antimicrobials
Step down to oral once tolerating PO intake and improving
Beta-lactams including cephalexin, cefuroxime, cefixime, amoxicillin, and amoxicillin-clavulanate may be used if susceptible but require 14d of therapy
TMP-SMX is preferred when susceptible for a duration of 7-10 days
Fluoroquinolones may be used for a duration of 7 days
Fosfomycin and nitrofurantoin can NOT be used for pyelonephritis due to inadequate tissue penetration
Ertapenem should generally be used for ESBL pyelonephritis
