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Guidelines
Pathogens
Antimicrobials
Medium
NA
$50/day
1g IV q24h
Targeted therapy of ESBL infections and other resistant gram negative infections
Empiric therapy when broad spectrum of carbapenems is desired without the need for anti-pseudomonal activity
Immediate and delayed-type allergy
GI disturbance
Cytopenias, eosinophilia, positive Coombs
Liver enzyme abnormalities
Seizure risk lower than other carbapenems
Requires ID approval
Antimicrobial class: Carbapenem
Pregnancy category: B
Average serum half life: 4.0
Biliary penetration: Moderate
Lung penetration: Therapeutic
Urine penetration: Therapeutic