Spectrum: Local Antimicrobial Stewardship, for Prisma Health Children’s Hospital-Midlands

Type I Reaction

Symptoms May Include

  • Anaphylaxis

  • Angioedema

  • Wheezing

  • Laryngeal edema

  • Hypotension

  • Hives/Uticarial

OR

  • Unknown reaction WITHOUT muscosal involvement, skin desquamation or organ involvement

Recommendations

Penicillin Allergy Skin Testing

OR

Use alternative agent based on appropriate coverage or contact ASP/ID¹

Note

¹ If skin testing is declined by caregiver or provider; do not de-label in these situations.