Spectrum: Local Antimicrobial Stewardship, for Prisma Health Children’s Hospital-Midlands

EOS ≥ 35 Weeks’ Gestation

Risk of Early-Onset Sepsis

Assess probability of sepsis based on objective data known at birth using calculator available here.

Note, for this calculation please select 0.5/1000 as the incidence of EOS at Children's Hospital-Midlands.

Classification of Infant's Clinical Presentation After Clinical Exam

Well Appearing

No persistent physiologic abnormalities

Equivocal

Persistent physiologic abnormality > 4 hrs

OR

Two or more physiologic abnormalities lasting for > 2 hrs. Note: Abnormality can be intermittent

  • Tachycardia (HR > 160)

  • Tachypnea (RR > 60)

  • Temperature instability (> 100.4˚F or < 97.5˚F)

  • Respiratory distress (grunting, flaring, or retracting) not requiring supplemental O₂

Clinical Illness
  1. Persistent need for CPAP / NC / mechanical ventilation ≥ 2 hours (outside of the delivery room)
  2. Hemodynamic instability requiring vasoactive drugs
  3. Neonatal encephalopathy / Perinatal depression

  • Seizure

  • Apgar Score @ 5 minutes < 5

Select Risk Result

Dependent on classification after clinical exam.

Note

  • Risk score does not apply if patient is clinically ill.

  • Please select "≥ 3/1000" for those patients.

< 1/1000

1-2.9/1000

≥ 3/1000