Spectrum: Local Antimicrobial Stewardship, for Prisma Health Children’s Hospital-Midlands

CDI First Recurrence

Vancomycin in tapered and pulsed regimen

Vancomycin 10 mg/kg (max: 125mg) 4xdaily x 14 days

THEN

Vancomycin 10 mg/kg (max: 125mg) 2xdaily x 7 days

THEN

Vancomycin 10 mg/kg (max: 125mg) daily x 7 days

THEN

Vancomycin 10 mg/kg (max: 125mg) every 2 days for 4wk

Additional Recommendations

Discontinuing Other Medications