Spectrum: Local Antimicrobial Stewardship, for Prisma Health Children’s Hospital-Midlands

Severe

Severe

  • Failure of oral antibiotics

  • Immunocompromised

  • Rapid progression of erythema

  • Systemic signs of infection

  • Temp >38°C

  • Tachycardia

  • Tachypnea

  • Abnormal white blood cell count

Surgical Procedure

Incision & Drainage

Initial Empiric Treatment

Vancomycin IV

PO Switch

May switch to PO if tolerating PO, afebrile and signs of skin infection improving

Patients ≥ 30 days

Patients < 30 days old