Spectrum: Local Antimicrobial Stewardship, for Prisma Health Children’s Hospital-Midlands

Non-Purulent

Common Pathogens

Beta hemolytic streptococci

Choose Severity

Mild

No signs of systemic infection

Moderate

Failure of oral antibiotics or systemic signs of infection:
- Temp >38°C
- Tachycardia
- Tachypnea
- Abnormal white blood cell count

Severe

Immunocompromised or clinical signs of deeper infection:
- Bullae
- Skin sloughing
- Hypotension
- Evidence of organ dysfunction
- Possible Toxic Shock Syndrome (TSS)

De-Escalation

Once susceptibilities are available, de-escalate to narrowest spectrum PO antibiotic