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Added Pleural Infection chapter
Pathogen-Directed Therapy for Pneumonia chapter was mistakenly removed during update to CAP chapter, has now been re-released
Cleaned up internal references to Vancomycin and Aminoglycoside Dosing and Therapeutic Monitoring documents
Acyclovir dosing in BMI>30 changed to adjusted body weight
Updated Urinary Tract Infections (UTI) chapter
Revised terminology of acute simple cystitis, acute complicated UTI, and special populations with unique features.
Revised diagnosis section to improve clarity.
Added optional one-time dose of parenteral antibiotic before starting oral therapy in non-severely ill acute complicated UTI.
Revised treatment recommendations for acute complicated UTI – severely ill.
Revised treatment duration for acute complicated UTI to 7 days in females and 10-14 days in males.
Limited amoxicillin-clavulanate and piperacillin-tazobactam in ESBL-producing organisms to acute simple cystitis only.
Added Aminoglycoside Dosing and Therapeutic Monitoring chapter
Added Penicillin Allergies
Added C. difficile infection (CDI)
Updated Antimicrobial Dosing in Renal Insufficiency (Adults) chapter to align recommendations with BC Provincial Renal Agency document “Common Oral Antimicrobial Therapy Dosage Adjustments for Renal Function” dated Feb 2018
Added Hospital-acquired pneumonia (HAP)
Added Ventilator-associated pneumonia (VAP)
Added Intra-abdominal infection (IAI)
Updated Community-acquired pneumonia (CAP) chapter
Added Skin and soft tissue infections (SSTI)
Added Diabetic foot infections (DFI)
Updated Pediatric Empiric Antibiotic guide