Spectrum: Local Antimicrobial Stewardship, for Billings Clinic

De-escalation

Note

Narrow agents based on culture and sensitivity results

If E. coli is susceptible to Cefazolin, de-escalate:

Cefazolin 2g IV q8h

Transition to PO

Transition to PO agent of the same class, if possible, e.g:

  • Ceftriaxone to Cefdinir

  • Cefazolin to Cephalein