Spectrum: Local Antimicrobial Stewardship, for IWK Health Centre

Acute Uncomplicated Pyelonephritis (Non-Pregnant)

Most likely pathogens

Suggested Regimen

Co-trimoxazole 800 mg/160 mg (1 DS tablet) PO q12h x 10-14 days

OR

Ciprofloxacin 500 mg PO q12h x 7 days

Unable to use Co-trimoxazole or Ciprofloxacin

Amoxicillin/clavulanate 500 mg PO q8h x 10-14 days

Penicillin Allergy

Ciprofloxacin 500 mg PO q12h x 7 days

OR

Co-trimoxazole 800 mg/160 mg (1 DS tablet) PO q12h x 10-14 days