Sinusitis (Acute Bacterial): Fever > 39 degrees or TREATMENT FAILURE WITH AMOXICILLIN (symptoms not resolved after 3-5 days)

Most likely pathogens

Haemophilus influenza

Streptococcus pneumoniae

Streptococcus pyogenes

Moraxella catarrhalis

Duration of therapy

7-10 days

Suggested regimen

Dosing is based on amoxicillin component:
Amoxicillin-Clavulanate 15-20 mg/kg/dose PO TID
Use the 80 mg/mL (7:1) formulation only

Penicillin allergy

If the patient has NOT had a previous IgE mediated reaction to amoxicillin:
Cefprozil 15-30 mg/kg/24h PO divideddaily- BID
Maximum: 1 gram/24h