Spectrum: Local Antimicrobial Stewardship, for IWK Health Centre

Community-Acquired Pneumonia Pregnancy

Most likely pathogens

Duration of Therapy

5-7 days including oral conversion

Note

During influenza season, ensure viral NP swab sent and initiate oseltamivir if clinically indicated

Suggested Regimen

Ceftriaxone 1 g IV q24h

AND

Azithromycin 500 mg PO x 1 dose on Day 1, then 250 mg PO q24h on Days 2-5 OR
Azithromycin 500 mg IV q24h x 2 days, then 250 mg PO q24h on Days 3-5

Oral Conversion

Amoxicillin 1000 mg PO q8h

OR

If comorbidities/modifying factors:

Cefprozil 500 mg PO q12h

+/-

Azithromycin 500 mg/dose PO day 1, then 250 mg/dose PO once daily on days 2-5

Penicillin Allergy

Ceftriaxone 1 g IV q24h

AND

Azithromycin 500 mg PO x 1 dose on Day 1, then 250 mg PO q24h on Days 2-5 OR
Azithromycin 500 mg IV q24h x 2 days, then 250 mg PO q24h on Days 3-5