Spectrum: Local Antimicrobial Stewardship, for Alberta Children's Hospital

Zanamivir

Not available in Canada

As of November 2018, IV zanamivir is not available in Canada, please check with Infectious Diseases service and pharmacy for any updates on this

Usual Route of Administration

  • Oral inhalation

  • Intravenous (By special access only)

Dose Adjustment on Renal Impairmant

Not required

Adverse Events

More Common

  • Bronchitis

  • Bronchospasm

  • Cough

Less Common

  • Allergic reactions with oropharyngeal or facial edema reported

  • Nausea

  • Diarrhea

  • Sinusitis

  • Nasal signs and symptoms

  • Headache

  • Dizziness

  • Ear, nose and throat infections

Comments

IV product is investigational

Special access reserved for hospitalized patients with severe influenza.

Requires both Health Canada Special Access Programme (SAP) approval and approval by manufacturer.