Home
Guidelines
Pathogens
Antimicrobials
Give single dose 30-60 minutes before procedure
If the antibiotic is inadvertently not administered before the procedure, it may be administered up to 2 hours after the procedure.
Do not use cephalosporins in patients with a history of anaphylaxis, angioedema, or urticaria with penicillin.
If a patient is already receiving long-term antibiotic therapy with an antibiotic that is also recommended for IE prophylaxis, an antibiotic from a different class should be used.
Amoxicillin 2 g oral
Ampicillin 2 g IM or IV
OR
Cefazolin 1 g IM or IV
Ceftriaxone 1 g IM or IV
Cephalexin 2 g oral
Clindamycin 600 mg oral
Azithromycin 500 mg oral
Clarithromycin 500 mg oral
Clindamycin 600 mg IM or IV