Spectrum: Local Antimicrobial Stewardship, for UCLA Health

Cephalexin

C. diff Risk

Medium

Oral Bioavailability

Moderate

Approximate Cost

$

Spectrum Of Activity

General Spectrum of Activity

Spectrum Of Activity

General Spectrum of Activity

Antibiogram Data

Dosing

Adult

500 mg PO q6h

Renal - Adult

Dose reduction for CrCl < 30

Pediatric

General Information

Common Usage

Common Usage

Uncomplicated skin and soft tissue infection, MSSA infections

Drug Monitoring

Drug Monitoring

Clinical

  • Hypersensitivity

  • Diarrhea

  • Other GI effects

Adverse Effects

Adverse Effects

  • GI effects

  • Hypersensitivity reactions

  • C. difficile

Major Interactions

Major Interactions

Increases metformin levels

Pharmacology

Pharmacology

Antimicrobial class: First generation cephalosporin - oral

Pregnancy category: B

Biliary penetration: Moderate

CSF penetration: Poor

Lung penetration: Moderate

Urine penetration: Therapeutic