Spectrum: Local Antimicrobial Stewardship, for UCLA Health

Antibiotic Recommendations

Empiric Therapy

Indications for Empiric Therapy

Patients ≥ 36 Months of Age

Patients < 36 Months of Age, Immunocompromised or Sickle Cell Disease

Definitive Therapy

Antibiotics should be targeted towards the most likely pathogen or cultures

Typical Duration

Culture Negative Osteomyelitis

Normal Host
Cephalexin 100-150mg/kg/day divided Q8 hours

Immunocompromised
Per Infectious Disease recommendation