Spectrum: Local Antimicrobial Stewardship, for UCLA Health

Streptococcus pneumoniae

Precautions

Standard Precautions
Standard Precautions

Susceptibilities

General susceptibility

General Susceptibilities

Susceptibilities

Antibiogram Data

General Information

First Line Treatment

First Line Treatment

Penicillin-susceptible

  • Penicillin

  • Amoxicillin

Penicillin-resistant
Meningitis

  • Vancomycin + Ceftriaxone +/- Rifampin

Other infections

  • Levofloxacin

  • Vancomycin

  • Ceftriaxone

Alternate Treatment

Alternate Treatment

Penicillin-susceptible

  • Ceftriaxone

  • Macrolide

  • Clindamycin

  • Doxycycline

  • Fluoroquinolone

Penicillin-resistant

  • Linezolid

Pathogen information

Pathogen information

Encapsulated lancet-shaped gram positive diplococci

Epidemiology

Epidemiology

Normal flora and important cause of invasive disease, often vaccine preventable

Associated syndromes

Associated syndromes

Community-acquired pneumonia, bacteremia, and meningitis.

Many other syndromes possible but uncommon including endocarditis, MSK, etc

Additional Information

Additional Information

Invasive pneumococcal disease is a reportable disease