SAB

Infectious Diseases Consultation is recommended for all S. aureus bacteremias

Definitions

Positive blood culture results and all of the following:

  • Intravascular catheter source of infection (if present) removed within 5 days

  • Negative follow-up blood cultures 24-72 hours after initial positive culture

  • Defervescence within 72 hours of initial positive culture

  • Echocardiogram without evidence of endocarditis

  • No symptoms or signs of metastatic infection

  • No indwelling intravascular prosthetic devices

  • Positive follow-up blood culture for S. aureus, OR

  • Persistent fever, OR

  • Echocardiography with evidence of endocarditis, OR

  • Symptoms or signs of metastatic infection

Duration of Therapy

When calculating the duration of antimicrobial therapy, day 1 of therapy is the day where a documented negative blood culture is obtained.

Minimum 14 days of therapy.

Minimum 28 days, and tailor duration according to focus of infection and clinical progression.