Complicated UTI or Pyelonephritis

Note

Risk Factors for Complicated UTI

Male (cystitis or pyelonephritis)
Immunocompromised (including poorly controlled diabetes)
Sepsis in setting of suspected UTI
Recent instrumentation
Structural abnormality of urinary tract (including stones, lesions, etc.)

Indications for Hospitalization in Setting of Complicated UTI

Inability to tolerate oral intake
Suspected sepsis
Acute renal insufficiency
Urinary tract obstruction

Most Common Organisms

E. coli (50%)

P. mirabilis (20%)

Enterococcus faecalis (10%)

Pseudomonas aeruginosa

Providencia stuartii

Citrobacter spp.

Enterobacter spp.

Serratia spp.

Empiric Antimicrobial Regimens