Spectrum: Local Antimicrobial Stewardship, for Markham Stouffville Hospital

Penicillin G - Meningitis Specific Dosing

Neonates 0-7 Days of Age

80,000-150,000 units/kg/dose IV/IM q8h

Smaller doses and longer intervals of administration may be advisable for very low–birth weight neonates (less than 2000g).

Neonates 8-28 Days of Age

112,000 units/kg/dose IV/IM q6h

Smaller doses and longer intervals of administration may be advisable for very low–birth weight neonates (less than 2000g).

Infants and Children

66,500 units/kg/dose IM/IV q4h

Dose limit: 24 million units/day (4 million units/dose)

Adults

4 mU IV q4h