Spectrum: Local Antimicrobial Stewardship, for Markham Stouffville Hospital

Appendectomy

Common Pathogens

Anaerobic species (most common Bacteroides)

Aerobic gram-negative enteric organisms species (most common E. coli)

Regimen of Choice

Cefazolin 2g IV

Redosing interval

q4h

PLUS

Metronidazole 500mg IV

Redosing interval

q8h

β-lactam Allergy

Metronidazole 500 mg IV

Redosing interval

q8h

Gentamicin 5 mg/kg IV

Redosing Dose & Interval

2 mg/kg q6h

Post-op Antibiotics

None unless one of the following:

  • Perforation

  • Gangrene

  • Peritonitis

  • Abscess